MammaPrint is the first and only FDA-cleared breast cancer genomic test that classifies your cancer as having either a Low Risk or High Risk of recurrence. It examines 70 of your genes that have been proven to have the strongest association with breast cancer. It has been validated extensively in more than 12,000 patients worldwide.
Because it looks at the most breast cancer genes, MammaPrint is the only test of its kind that will give you a definitive result. There is no “intermediate” result that leaves you in limbo about whether you have a Low Risk or High Risk of recurrence or whether or not you will benefit from chemotherapy. The results are always either High Risk or Low Risk.
If your result comes back Low Risk, you have less than a 10% chance of your cancer returning in the next 10 years and there is little, if any, benefit to getting chemotherapy. Research has shown that by adding hormone therapy alone, your risk can be lowered to about a 5% chance of recurrence. See reference 1,2,3.
If you are in the High Risk category, you have a 29% chance of your cancer recurring if left untreated, and you should consider chemotherapy as part of your regimen. You should also consider having your subtyping performed in order to fine-tune your therapy.